CBD 101: A Complete CBD Education

CBD At a Glance

CBD is an abbreviation for “Cannabidiol”. Is one of 113 identified cannabinoids found in cannabis sativa. CBD extract is a mixture of multiple phytocannabinoid strains and a wide range of terpenes (plant pheromones).Though THC, CBD, and Terpenes work best when they are together (creating the “Entourage Effect”), the removal of THC does not hinder the benefits of the product in any way but does remove the psychoactive portion from the plant. The are no known major side effects from CBD. Although there are no known reactions with medication, as a general practice it is always good to consult with a medical doctor. CBD is completely safe for kids and for animals. Both kids and animals generally require smaller doses, but it is completely safe and beneficial for them in the same way it is beneficial to an adult. CBD strains help with different issues. One issue may be specific to CBDa, whereas another issue, in the same person, could be helped by a different CBD strain. If two issues are helped by the same strain, the effects may be less noticeable and dosage should most likely increase.

Consider Why Your Health Would Benefit from CBD

Cannabinoids such as CBD have a dizzying array of functions in the human body, influencing everything from inflammation to anxiety and depression. You don’t necessarily need to have a serious illness to benefit from CBD; even healthy individuals can experience a remarkable increase in their quality of life with its use.The following is a chart of illnesses/conditions that whose symptoms may be relieved by CBD:

Pain (neuropathic, chronic etc.)
EpilepsyMultiple Sclerosis (MS)
Amyotrophic Lateral Sclerosis (ALS)
Parkinson’s
Inflammation
Acne
Dyskinesia
Psoriasis
Broken Bones
Mad Cow Disease
Depression
Bacterial Infections
Diabetes
Rheumatoid Arthritis
Nausea
Anxiety
ADHD
Schizophrenia
Substance Abuse/Withdrawal
Heart Disease
Irritable Bowel Syndrome (IBS)

Keep in mind that this CBD benefits list is in no way complete; we are only beginning to discover how cannabinoids can help.

Cannabis VS Hemp Oil

The possession and consumption of CBD is legal but it depends on where it comes from. This is where the difference between hemp and cannabis comes in – the distinction is nothing more than a legal one. Cannabis itself is a genus of a flowering plant – in other words, the scientific name for the plant. Traditional cannabis – pot, weed, marijuana, whatever you want to call it – is typically bread for high THC content which provides the psychoactive effects. Alternatively, hemp is bred and grown for the industrial use of fiber and seed, which is why hemp must legally contain below 0.3% THC – so that it stays below the threshold of inducing psychoactivity.

We had a question if our product contained true CBD oil or Hemp oil?  This is a misleading question as CBD Oil and Hemp Oil are one in the same.  However, oil taken from the Hemp seed is only hemp seed oil whereas Hemp Oil from the entire plant is full spectrum and has each of the subcomponents of CBD.

Rare but Legitimate Health Concerns

Before you start taking CBD, please read about drug interactions.It is important to note that even something as benign as grapefruit juice can cause the same CYP450 enzyme inhibitory action as CBD.The most important things to do before taking any herbal product are to research any possible drug interactions and talk with your physician to address any additional questions regarding CBD drug interactions. You and your doctor together will always know best!  

Understand How Your Genetics Impact CBD Dosing

Some individuals have been found to have mutations on the CNR1 gene, which is responsible for coding the CB1 receptor (a type of receptor in cells throughout your body that interacts with cannabinoids). Issues with the CNR1 gene can ultimately result in a poorly functioning endocannabinoid system, which is an important variable when figuring out how to use CBD oil.

Rest Easy Knowing CBD Oil Is Not Physically Addictive

People often ask us, “Can I get addicted to CBD oil?” This is a tricky question, and the answer ultimately depends on your school of thought.Based strictly on chemistry, the answer is no. Cannabidiol is not physically addictive in the same way substances like heroin, cocaine, alcohol, opiates, benzodiazepines, and related substances can be. Further, CBD cannot produce any physical withdrawal symptoms in and of itself upon cessation of use. (Interestingly, CBD is currently undergoing study for its ability to minimize withdrawal from drugs with severe cessation symptoms, like opiates.) However, human beings can get addicted to just about anything that isn’t chemically addicting: exercise, music, sex, and food are great examples. Those who take CBD daily to relieve symptoms of chronic illness and other severe conditions may find that their unpleasant sensations return shortly after they miss a dose. This is no different than one’s headache returning once the effects of ibuprofen wear off.


Why CBD Works

The Endo-Cannanbanoid System:

We as humans have an endocannabinoid system rooted within our nervous system. Though your body does create endocannabinoids, we are naturally deficient. Adding Phytocannabinoids, or cannabinoids that come from a plant source, gives the body the ability to fill the variety of gaps that everyone has. Your body will pull the select strains of CBD that it needs, and apply them to the body.CBD acts as a therapeutic agent in your endocannabinoid system, constantly working to get your body into a place of homeostasis. As a naturally occurring molecule in your body to begin with, the consumption of CBD provides additional regulatory molecules to help your bodies physiological systems operate more efficiently.

A New Science

The recent identification of cannabinoid receptors has triggered an exponential growth of studies exploring the endocannabinoid system and its regulatory functions in health and disease. Such studies have been greatly facilitated by the introduction of selective cannabinoid receptor antagonists and inhibitors of endocannabinoid metabolism and transport, as well as mice deficient in cannabinoid receptors or the endocannabinoid-degrading enzyme fatty acid amidohydrolase. In the past decade, the endocannabinoid system has been implicated in a growing number of physiological functions, both in the central and peripheral nervous systems and in peripheral organs. More importantly, modulating the activity of the endocannabinoid system turned out to hold therapeutic promise in a wide range of disparate diseases and pathological conditions, ranging from mood and anxiety disorders, movement disorders such as Parkinson’s and Huntington’s disease, neuropathic pain, multiple sclerosis and spinal cord injury, to cancer, atherosclerosis, myocardial infarction, stroke, hypertension, glaucoma, obesity/metabolic syndrome, and osteoporosis, to name just a few.


How CBD Treats Certain Ailments

Anxiety, Stress and Depression

CBD binds to the HT1A serotonin receptors throughout the brain, and acts as a natural Selective Serotonin Reuptake Inhibitor (SSRI). Serotonin is the “happy hormone” in the body, and when we lack enough of this hormone we become stressed, anxious or depressed. What SSRIs do is prevent the reabsorption of serotonin, which in turn eliminates the symptoms of depression, anxiety and stress. Commonly prescribed SSRIs like Zoloft or Prozac are synthetic replicators of the desired effect that CBD naturally creates. On top of that, studies have shown that CBD is actually more effective, and faster, than its synthetic counterpart due to the fact that your body already recognizes the natural CBD chemical. Synthetic replicates are not initially recognized by the body, so they are typically less effective, take longer to work and can be harmful.- CBD also promotes neurogenesis within the hippocampus portion of the brain. Neurons responsible for communication with serotonin receptors can weaken or die out, and that can cause depression or anxiety. It was found in a Brazilian study that CBD actually assists the process of creating the new neurons that have died out.- CBD also helps the communication between neurons allowing for a more effective release of serotonin.

Pain: CBD was found to bind to what are known as 7 Domain G coupled proteins. G protein-coupled receptors (GPCRs) represent the largest and most diverse family of cell surface receptors and proteins. These receptors are most closely associated with the transmission of pain, and are targeted by many medications. CBD binds naturally to the GPCRs and does the exact same thing as certain pain medications alleviating pain symptoms.

Rheumatoid Arthritis: CBD was found to be something known as an “immunomodulator” meaning it can be used to help regulate or normalize the immune system. Since Rheumatoid Arthritis (RA) is an issue mostly rooted in the immune system, taking CBD can help with the symptoms.

Thyroid Issues: CBD binds to the Hypothalamic Paraventricular Nucleus (HPN), which is the part of the brain that sends signals to regulate the thyroids. CBD specifically attaches to the iodothyronine and Thyroxine enzymes. Both of those enzymes help with the release of hormones from the thyroid. This helps to keep the thyroid in balance especially for people with hyper and hypothyroid issues.

Acne: Acne is a common skin condition that affects more than 9% of the population. It is thought to be caused by a number of factors, including genetics, bacteria, underlying inflammation and the overproduction of sebum, an oily secretion made by sebaceous glands in the skin. Based on recent scientific studies, CBD oil may help treat acne due to its anti-inflammatory properties and ability to reduce sebum production. One test-tube study found that CBD oil prevented sebaceous gland cells from secreting excessive sebum, exerted anti-inflammatory actions and prevented the activation of “pro-acne” agents like inflammatory cytokines. Another study had similar findings, concluding that CBD may be an efficient and safe way to treat acne, thanks in part to its remarkable anti-inflammatory qualities

CBD Consumption Guide: Part 1

Because there is no recommended dose, the information presented on this page is intended to serve only as an informational guide – a starting point of reference – and should never be considered medical advice.

This is a two-part question as you are really asking who makes the best CBD products and which consumption method is best for me? The answer to the first part is easy – Purely CBD.  The answer to the second part of the question is a bit more personal as it depends on what effect you desire from the CBD – meaning someone who suffers from Rheumatoid Arthritis is going to have a different regimen than someone who uses CBD to manage anxiety.When evaluating different consumption methods, the primary differences will be whether the product provides systemic or localized relief, the onset time, and the relief duration. Systemic relief affects the whole body, whereas localized relied only affects the area to which the product was applied. That said, many conditions benefit from a multi-pronged approach where you treat a problem with a mix of products.  You could combat Rheumatoid Arthritis, for instance, with one CBD product to reduce systemic inflammation and another CBD product to treat the local joints. The other benefit to this complimentary product approach is that some products provide instant relief for a short amount of time, while others have a longer onset time but provide relief for the entire day.Below we will cover the different CBD consumption methods as well as the onset time and relief duration associated with each type of product.

Systemic Products

These products are a great way to get your desired daily dose of CBD. Many people find that a regular, daily dose of CBD is great for prevention and management. Alternatively, a larger dose can be used to treat flare ups. The following products provide systemic relief for several hours – they are especially helpful for those suffering from anxiety, depression, and immune system issues.

Tinctures

A tincture is a liquid CBD concentrate that is applied under the tongue. Historically, tinctures were alcohol based; however, we recommend a coconut/MCT oil based tincture that allows the CBD oil to be easily absorbed by the body. The solution is absorbed by the arterial blood supply under the tongue within seconds, but the full extent of the effects can take up to an hour to be felt. Holding the liquid under the tongue allows for faster absorption through the bloodstream as opposed to processing through the gastrointestinal (GI) tract. Tinctures and gel caps provide the longest duration of relief. – anywhere from 4 to 8+ hours depending on the individual.

Gel Caps

Gel caps contain a CBD extract in an organic MCT coconut oil carrier. They are a form of ingestible CBD – very similar to tinctures – the primary difference is form factor. Gel caps provide sustained, systemic relief for several hours. The downside to gel caps is the hour plus onset time – certainly the longest of any of the consumption options (because the CBD is not immediately absorbed under the tongue like a tincture). Many people like the gel caps because it feels like they are taking a normal pill, which they are already comfortable doing. The gel caps and tinctures are generally interchangeable – just be mindful of the slight difference in onset time.

Localized CBD Products

As the name indicates, these products only affect the area where the product was applied – as such, this class of products is often referred to as simply ‘topicals’. Some only impact the skin layer to which they are applied, while others penetrate into the muscle and joints underneath the skin.

Salves/Rubs

Salves are CBD infused topical creams that are applied directly to the skin for localized relief of pain and inflammation, making them perfect for treating muscle, joint, and surface-oriented pain. The CBD goes to work immediately after rubbing the salve onto the affected area and relief can be felt in as little as 15 minutes. Salves provide relief for hours; simply re-apply as necessary.  Salves are best for those suffering from general aches, pains, soreness, and any form of arthritis.

Sprays

Sprays are another form of CBD infused topical that are sprayed directly to the skin – this application method is preferred by those suffering from painful skin conditions like eczema, and psoriasis. These sprays are gentle and don’t leave behind the same oily consistency some salves leave behind – making them better suited for treating burns, rashes, and other skin irritation. Some sprays even act as beauty products to help reduce wrinkles, and rejuvenate the skin.

Soaks

Soaks refer to CBD infused bath salts that induce a calming and soothing effect. Often times they are infused with aromatic essential oils to make your bath even more enjoyable. Soaks are best for those looking to relax their body and sooth their skin.


CBD Consumption Guide: Part 2

How Much CBD Oil Should I Take?

Mayo Clinic suggests CBD dosages based on scientific research, publications, traditional use, and expert opinion. Cannabinoid dosages and duration of treatment depend mainly on the illness (and countless other factors).

The following chart from Mayo Clinic provides specific dosage recommendations for various illnesses:

Loss of Appetite in Cancer Patients: 2.5mg of THC (orally), with or without 1mg of CBD for six weeks.

Chronic Pain: 2.5-20mg of CBD [with or without THC] (orally). [S]

Epilepsy: 200-300mg of CBD (orally) daily. [S]

Movement Problems Due to Huntington’s Disease: 10mg of CBD per kg of body weight daily for six weeks (orally). [S]

Sleep Disorders: 40mg-160mg of CBD (orally). [S]

Multiple Sclerosis (MS) symptoms: Cannabis plant extracts containing 2.5-120 milligrams of a THC/CBD combination daily for 2-15 weeks. Patients typically use eight sprays within any three hours, with a maximum of 48 sprays in any 24-hour period. [S]

Schizophrenia: 40-1,280mg oral CBD daily. [S]

Glaucoma: A single sublingual CBD dosage of 20-40mg (>40 mg may increase eye pressure). [S]